报 告 内 容 简 介 |
报告人简介： Professor Sixue Chen completed his Ph.D. study in plant biochemistry in China, and postdoctoral research in Germany, Denmark and University of Pennsylvania, USA. He was a Professor in Genetics Institute, and Director of Proteomics and Mass Spectrometry Facility at University of Florida. Dr. Chen is now Professor and Chair of Department of Biology at the University of Mississippi. He has established three major research projects: plant guard cell disease triangle, glucosinolate metabolism, and photosynthesis transition from C3 to CAM. His lab is known for application of single-cell type proteomics and mass spectrometry technologies in elucidating plant molecular networks. He has been continuously funded by NSF, USDA, NIH and University internal funds and has more than 300 publications. Dr. Chen serves as Associate Editors and/or Board Members of Archives of Proteomics and Bioinformatics, BBA - Proteins and Proteomics, Frontiers in Plant Proteomics, International Journal of Molecular Sciences, Journal of Proteomics, Metabolomics, Proteomes, and other journals. He is an elected Fellow of the American Association for the Advancement of Science. 报告内容简介： How stomatal guard cells respond to pathogen invasion and other environmental factors (e.g., rising CO2 levels) is an important and interesting question. Recently, we have reported a new redox proteomics method called cysTMTRAQ that combines two types of isobaric tags, isobaric tag for relative and absolute quantification (iTRAQ) and cysteine tandem mass tag (cysTMT) in one experiment. Here I report the functional characterization of a lipid transfer protein in guard cell innate immunity. As CO2 levels affect stomatal immunity and stomatal movement, we studied CO2 signaling using hyphenated metabolomics technologies. A new signaling pathway involving jasmonic acid was discovered. Future directions in signal crosstalk and data integration in the context of stomatal disease triangle will be discussed. |
