【通知公告】【生命学院】学术讲座系列:卢挺关于Bottom-up Assembly of Microbial Communities: Modeling, Analysis and Engineering的讲座
发布者:
发布日期:2020-01-03
浏览次数:
报告题目 |
Bottom-up Assembly of Microbial Communities: Modeling, Analysis and Engineering |
报 告 人 |
卢挺 博导 |
报告时间 |
2020年1月8日14:00-15:00 |
报告地点 |
生命科学学院D570 |
报 告 内 容 简 介 |
Microbial communities are fundamentally important to human health, environment and agriculture. To realize their potential for various applications, a fundamental challenge is to decipher the basic rules that govern microbial organization in space and time. My lab aims to address the challenge using a bottom-up approach that combines biophysical modeling with experimental synthetic biology. Recently, we developed a computational platform that enables individual-based simulation of microbial communities across multiple scales. Using the platform, we investigated how the modes of cellular social interactions and the spatial scale of interaction contribute to microbial assemblages, both of which were also examined using experimental ecosystems. Using engineered cellular interactions, we further demonstrated the utility of synthetic consortia for applications in metabolic engineering. Our studies provide insights into the organization of microbial communities, and illustrate the potential of synthetic ecosystems for practical purposes.
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承办单位 |
生命科学学院 |
发布日期 |
2020.1.3 |
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